FENBENDAZOLE UN ANTIPARASITE POUR DETRUIRE LE CANCER FENBENDAZOLE AN ANTIPARASITE TO DESTROY CANCER
Le fenbendazole
J'ai découvert le fenbendazole en tant qu'antiparasitaire. Un ami médecin le prescrivait deux fois par an aux enfants et aux adultes, tout comme on donne des vermifuges aux animaux. Eh bien, aujourd'hui, ce médicament surprenant fait parler de lui au-delà de son rôle initial ! Comme d'autres antiparasitaires, de nombreuses personnes commencent à le considérer comme un puissant allié dans la lutte contre le cancer. Incroyable, non ? Bien sûr, il est essentiel de le doser correctement. (Certains essais à faible dose seraient même conçus pour discréditer ses véritables effets).**
The Fenbendazole
I first discovered fenbendazole as an antiparasitic. A doctor friend of mine used to prescribe it twice a year to both children and adults, much like we give dewormers to animals. Well, today, this amazing drug is making waves far beyond its initial purpose! Like other antiparasitics, many people are now seeing fenbendazole as a major anti-cancer treatment. Incredible, right? Of course, it's crucial to administer it at the right dose. (Some trials with low doses may even be intentionally designed to discredit its true effects).
D Park, JH Lee, SP Yoon - … Society and the Korean Society of …, 2022 - synapse.koreamed.org
… Flow cytometry revealed that fenbendazole … that fenbendazole may be a potential alternative treatment in 5-fluorouracil-resistant cancer cells, and the anticancer activity of fenbendazole …
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N Dogra, A Kumar, T Mukhopadhyay - Scientific Reports, 2018 - nature.com
… Fenbendazole is known to have a high safety margin and most species tolerate it very … fenbendazole (FZ) exhibits a moderate microtubule depolymerizing activity towards human cancer …
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CS Chang, JY Ryu, JK Choi, YJ Cho… - Journal of …, 2023 - ncbi.nlm.nih.gov
… Fenbendazole (FZ) has potential anti-cancer effects, but its poor water solubility limits its use for cancer therapy. In this study, we investigated the anti-cancer effect of FZ with different …
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Q Duan, Y Liu, CJ Booth… - Journal of the American …, 2012 - ingentaconnect.com
… fenbendazole … Cancer Research3 reported that high doses of fenbendazole, albendazole, and mebendazole inhibited the growth of paclitaxel-resistant tumors. Because fenbendazole …
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Y Han, HG Joo - Korean Journal of Veterinary Research, 2020 - kjvr.org
… anti-cancer effects related to disruption of microtubule polymerization. In this study, we investigated whether FBZ has anti-cancer … This study provides evidence that FBZ has anti-cancer …
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S Semkova, B Nikolova, I Tsoneva, G Antov… - Anticancer …, 2023 - ar.iiarjournals.org
… The redox-modulating properties of fenbendazole in cancer … fenbendazole on cancer and normal cells of the same origin. … of breast cancer cells by fenbendazole without affecting the …
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Q Duan, Y Liu, S Rockwell - Anticancer research, 2013 - ar.iiarjournals.org
… Conclusion: These studies provided no evidence that fenbendazole would have value in cancer therapy, but suggested that this general class of compounds merits further investigation. …
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… Fenbendazole (FBZ) is a benzimidazole anthelmintic agent that has been used safely for … This mechanism is similar to that of anticancer drugs targeting microtubules in cancer cells, …
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JY Sung, HG Joo - Prev. Vet. Med, 2021 - e-sciencecentral.org
… Fenbendazole (FBZ) is one of the safest anthelmintic drugs. FBZ has been found to have anti-cancer … (PA), a microtubule-stabilizing anti-cancer agent, and FBZ was investigated on HL-…
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JJ Noh, Y Cho, J Choi, J Shim, Y Lee - 대한부인종양학회 학술대회지, 2021 - kiss.kstudy.com
… may serve as potential anti-cancer candidates. Fenbendazole is a broad-spectrum benzimidazole … the inhibitory activity of fenbendazole towards human ovarian cancer cells and animal …
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Journal Article•DOI
Kyung-Sun Kang +1 more
15 Jun 2022-Cancer Research
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Open access•Journal Article•DOI
YouJin Lee +1 more
31 Mar 2023-Korean journal of veterinary research
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09 Aug 2018-Scientific Reports
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17 Feb 2022-Anti-cancer Agents in Medicinal Chemistry
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01 Dec 2021-Cancer Letters
5 Citations
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01 Jan 2018-Anti-cancer Agents in Medicinal Chemistry
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Keum Gyo Chang +4 more
· "Fenbendazole as an Anticancer Agent: A Review"
Auteurs : Zhang et al.
Journal : Frontiers in Oncology (2021)
Résumé : Cet article passe en revue les études existantes sur le potentiel anticancéreux du fenbendazole, discutant des mécanismes possibles et des résultats cliniques préliminaires.
· "Fenbendazole: A Novel Approach for Cancer Treatment?"
Auteurs : Silva et al.
Journal : Journal of Cancer Research and Therapeutics (2020)
Résumé : L'article explore les recherches récentes sur le fenbendazole et ses effets sur divers types de cancer, avec un accent sur les mécanismes d'action et les études précliniques.
· "Anticancer Properties of Fenbendazole in Preclinical Models"
Auteurs : Patel et al.
Journal : Cancer Chemotherapy and Pharmacology (2019)
Résumé : Cette étude examine les effets du fenbendazole dans des modèles animaux de cancer, incluant des résultats sur l'efficacité et les mécanismes sous-jacents.
· "Evaluation of Fenbendazole as a Cancer Therapeutic: A Systematic Review"
Auteurs : Lee et al.
Journal : European Journal of Pharmacology (2022)
Résumé : Une revue systématique qui compile les données disponibles sur le fenbendazole et son potentiel en tant que traitement anticancéreux.
· "Mechanisms of Fenbendazole Action in Cancer Cells: Evidence from In Vitro Studies"
Auteurs : Nguyen et al.
Journal : Molecular Cancer Therapeutics (2023)
Résumé : Cet article se concentre sur les mécanismes par lesquels le fenbendazole pourrait affecter les cellules cancéreuses, basé sur des études in vitro.
Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer (Chang et al., 2023) Demonstrates enhanced anti-cancer efficacy of fenbendazole in EOC using nanoparticle delivery systems -
2 Redox-mediated Anticancer Activity of Anti-parasitic Drug Fenbendazole in Triple-negative Breast Cancer Cells (Semkova et al., 2023) Explores fenbendazole's selective oxidative stress induction in triple-negative breast cancer cells -
3 Fenbendazole induces cell cycle arrest in colorectal cancer cells and patient-derived colon cancer organoids (Kang & Kim, 2022)
| Demonstrates enhanced anti-cancer efficacy of fenbendazole in EOC using nanoparticle delivery systems | - |
2 | Explores fenbendazole's selective oxidative stress induction in triple-negative breast cancer cells | - |